G442S : Mutation rate in yeast

The Saccharomyces cerevisiae pol3-G447S mutation mimicking human POLD1-G442S does not increase the mutation rate.

• Hadjimarcou, M. I. et al. Identification of a mutant DNA polymerase δ in Saccharomyces cerevisiae with an antimutator phenotype for frameshift mutations. Genetics 158, 177-186 (2001). https://pubmed.ncbi.nlm.nih.gov/11333228/