P608S : Mutation rate in yeast

The Saccharomyces cerevisiae pol3-P614S mutation mimicking human POLD1-P608S increases the mutation rate in MSH6-deficient strains.

• Herr, A. J. et al. Mutator suppression and escape from replication error-induced extinction in yeast. PLoS Genet 7, e1002282 (2011). https://pubmed.ncbi.nlm.nih.gov/22022273/