R742H : Mutation rate in yeast
The Saccharomyces cerevisiae pol2-R758H mutation mimicking human POLE-R742H does not affect the mutation rate.
References
- Ostroverkhova, D. et al. DNA polymerase ε and δ variants drive mutagenesis in polypurine tracts in human tumors. Cell Rep 43, 113655 (2024) https://pubmed.ncbi.nlm.nih.gov/38219146/