S297F : Mutation rate in yeast

Saccharomyces cerevisiae strains heterozygous for the pol2-S312F mutation mimicking human POLE-S297F have a mutator phenotype.

• Herzog, M. et al. Mutagenic mechanisms of cancer-associated DNA polymerase ε alleles. Nucleic Acids Res 49, 3919-3931 (2021). pubmed.ncbi.nlm.nih.gov/33764464/