V474I : Mutation rate in yeast

The Schizosaccharomyces pombe pol2-V475I mutation mimicking human POLE-V474I elevates the mutation rate.

• Esteban-Jurado, C. et al. POLE and POLD1 screening in 155 patients with multiple polyps and early-onset colorectal cancer. Oncotarget, 8, 26732-26743 (2017). https://pubmed.ncbi.nlm.nih.gov/28423643/